Peritoneal Cryptococcosis in a Dog

Background: Cryptococcosis is an opportunistic, systemic mycotic disease caused by a yeast of Cryptococcus neoformans. These pathogens cause serious public health problems, as they can be transmitted to humans, domestic and wild animals. In cats dogs, the main site infection upper lower respiratory tract, however, extend affect other sites in organism, peritoneal manifestation rare. Thus, present work aims report case cryptococcosis canine, mixed breed, female, adult, from Metropolitan Region Belém.Case: A breed dog, adult was admitted veterinary hospital at Belém, presenting abdominal discomfort and, after clinical examination, emergency exploratory laparotomy indicated, it were observed disseminated lesions cavity, with multiple nodules attached peritoneum intestinal serosa bladder, uterus, among organs. Fragments surgical biopsy fixed, processed routinely according techniques for histological tissue processing. Histological examination revealed predominance granulomatous mesentery It discrete inflammatory reaction macrophages, epithelioid cells giant cells, many phagocytosis spherical or ovoid organisms, thick capsule clear perinuclear halo. PAS staining, conidia presented eosinophilic characteristics some them had well demarcated, which shown radiated. Also possible see budding Grocott stain, stained black.Discussion: involvement animals rarely reported literature. agent that presents tropism central nervous system nasal however atypical presentations have been reported, especially level cavity (intestines mesentery). believed gastrointestinal tract gateway ascending contamination, contamination occur fungal ingestion. The distribution, isolated coalescent adhered adjacent structures. literature reports two cases dogs intra-abdominal cryptococcosis, which, macroscopically, formations jejunum, lymph nodes mesentery. Microscopically, infiltrate macrophages lymphocytes observed. Some areas reaction, lymphocytes, areas, yeasts cytoplasm ovoid, surrounded polysaccharide. periodic acid Schiff (PAS) silver impregnation (Grocott) staining used highlight structures wall strong polysaccharide capsule. must emphasized zoonotic potential both humans. humans normally occurs when fungus accesses airways through inhalation ranges asymptomatic pulmonary colonization compromised meninges, causing human patient's life-threatening condition. report, diagnosis established histopathological histochemical structure, determinant etiological cryptococcosis.